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Neuroscientist Janika Ruuska opens up about her 11-year battle with anorexia nervosa, describing how seemingly harmless health choices gradually spiraled into a severe eating disorder fueled by feelings of unworthiness and perfectionism. She sheds light on the psychological aspects of anorexia, explaining how initial weight loss reinforcement can lead to a destructive cycle of self-punishment and rigid thinking.
She also highlights the alarming mortality rate associated with anorexia and the lack of approved pharmacological treatments, pointing to the role of serotonin signaling in the disorder. As a potential breakthrough, she introduces psilocybin, a psychedelic therapy recognized by the FDA, which may help improve cognitive flexibility.
The video further explores a study on psilocybinās effects in an animal model, which revealed changes in serotonin receptors linked to anorexia but no significant treatment outcomes, suggesting that more research is needed to refine dosage and timing. Janika also considers the potential benefits of combining MDMA with other therapies to promote self-compassion, while acknowledging the health risks this approach may pose for individuals with anorexia.
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